Materials Science Unit, Chemistry Department ,Faculty of Science, Tanta University-31725, Tanta, Egypt
Gramicidin ,Nano-Structural Features ,3D-AFM ,Grains Size ,Surface ,

The present investigations discuss the 3D-AFM nano-structural features of gramicidine –A trying to link between its nano-structural properties and its applications. The branching of polypeptide linkage of gramicidine needs special stereo – orientation to be applied as therapeutic antibacterial cream or ointment .The present 3D-AFM- investigations introduce important conclusive remarks enhance scientific community to understand why gramicidin family as antibiotic cream or ointment are structurally suitable with special surface topography enhance it to be applied as cream or ointment .Poly-peptide linkage chains have high flexibility factor with maximum degree of freedom to be bend or rotates.

5 , 1 , 2015