Assistant Professor, Department of Dermatology, Viswabarathi Medical College & General Hospital, RT Nagar, Penchikalapadu, Kurnool, India.
Macular amyloidosis, Epstein-Barr virus, Eosinophilic Hyaline Precipitate, PCR ,

An eosinophilic hyaline precipitate and special staining features are symptomatic of amyloidosis. Macular amyloidosis, which occurs only on the skin, is a result of several different factors. Considering that Epstein-Barr virus (EBV) was detected in this lesion, it seems likely that it could factor into the pathogenesis of this disease. The purpose. The EBV DNA was detected with PCR in 30 samples from patients with macular amyloidosis and 31 healthy samples taken from the margins of melanocytic nevi removed from patients. Results. Twenty-three patients tested positive for the BLLF1 gene of EBV in the control and eight in the case groups. A significant difference in EBV DNA levels was not observed between macular amyloidosis or control groups (P<0.08). Based on the findings of this study, EBV does not cause macular amyloidosis

12 , 2 , 2022