Associate Professor, Aadhibhagawan College of Pharmacy, Rantham Village, Cheyyar, Thiruvannamalai Dist, Tamil Nadu, India.

Aadhibhagawan College of Pharmacy, Rantham Village, Cheyyar, Thiruvannamalai Dist, Tamil Nadu, India

Aadhibhagawan College of Pharmacy, Rantham Village, Cheyyar, Thiruvannamalai Dist, Tamil Nadu, India

Aadhibhagawan College of Pharmacy, Rantham Village, Cheyyar, Thiruvannamalai Dist, Tamil Nadu, India

Aadhibhagawan College of Pharmacy, Rantham Village, Cheyyar, Thiruvannamalai Dist, Tamil Nadu, India
Ivermectin ,Anthelminthic drug ,Bacteriostatic ,

The avermectins are a newly discovered class of macrocyclic lactones isolated from Streptomyces avermitilis that have insecticidal, acaricidal, and anthelmintic activity. Ivermectin (MK-0933) is a parasiticide that is the -dihydro derivative of avermectin Bl. It is used in a variety of animal species, including humans. Ivermectin is a semisynthetic derivative of ivermectin B1 that is made up of an 80:20 mixture of the equipotent homologous. When IVM acts as a bacteriostatic agent, it is advantageous because bacteriostatic antibiotics can avoid some of the drawbacks associated with bactericidal drugs. For example, when bactericidal drugs kill bacteria, endotoxins are released that may be toxic to the host, whereas bacteriostatic drugs inhibit bacterial growth, allowing the host to elicit protective immunity and thus result in immunological clearance of the bacteria Although the efficacy of ivermectin against several parasitic diseases has been established in humans, the pharmacokinetic properties of this compound in humans are less well understood than in animals. Ivermectin has potential drug-drug interactions and drug-food interactions that should be considered during therapeutic use

12 , 1 , 2022