Institute of Pharmacology, Madurai Medical College, Madurai-625020, Tamilnadu, India

Joint Directorate of Medical Education (Pharmacy), Kilpauk, Chennai-600 003, Tamilnadu, India

Institute of Pharmacology, Madurai Medical College, Madurai-625020, Tamilnadu, India
Hydro alcoholic extracts of Ipomoea pes-tigridis ,Glycogen content ,Glucokinase ,Hexokinase ,Glucose-6- phosphate ,Diabetes mellitus ,

The antihyperglycemic effect of hydroalcoholic extracts of (Ipomoea Pes-tigridis) was evaluated in diabetic rats using Alloxan monohydrate(150mg/kg) as diabetogenic agents for pilot study (4 weeks)so as to assess their effect in mild (plasma sugar more than 160mg/dl)diabetes mellitus. In the pilot study maximum reduction of 67.2% and 66.3 % glucose levels was observed in animals receiving 200mg/kg and 400mg/kg per day of Hydro alcoholic extracts of (Ipomoea Pestigridis) after 4 weeks of treatment, respectively. The alteration in hepatic glycogen content and hepatic glucokinase, hexokinase and glucose-6- phosphate levels in diabetic rats were partially restored by Hydro alcoholic extracts of (Ipomoea Pes-tigridis).

6 , 1 , 2016