Sree Vidyanikethan College of Pharmacy, Tirupati, Andhra pradesh – 517102, India.

Sree Vidyanikethan College of Pharmacy, Tirupati, Andhra pradesh – 517102, India.

Sree Vidyanikethan College of Pharmacy, Tirupati, Andhra pradesh – 517102, India.

Sree Vidyanikethan College of Pharmacy, Tirupati, Andhra pradesh – 517102, India.
Diabetic neuropathy , Pain and trophic ulcers ,Treatment ,

More than 80% of patients with clinical diabetic neuropathy have a distal symmetrical form of the disorder. In this neuropathic pattern, signs and symptoms start and remain more pronounced in the feet, and go on to affect more-proximal parts of the lower limbs and eventually the distal parts of the upper limbs, indicating that the longest nerve fibers are affected first. Shorter sensory axons subsequently become involved, accounting for neuropathic manifestations in more-proximal parts of the limbs and eventually the anterior trunk. This is often referred to as a length-dependent pattern. In this review, I will consider the clinicopathological aspects of the various patterns of diabetic neuropathy, starting with diabetic polyneuropathy, which is by far the most common type of diabetic neuropathy. I will also consider the focal diabetic neuropathies, and discuss the diagnosis of chronic inflammatory demyelinating polyneuropathy, which should not be missed or confused with diabetic neuropathy when it occurs in patients with diabetes

2 , 1 , 2012