e ISSN- 2249-7668

Print ISSN- 2249-7676

ISSN

2249-7676

e ISSN

2249-7668

Publisher

pharmacology and toxicology

EVALUATION OF ANTIMICROBIAL ACTIVITY OF CATUNAREGUM SPINOSA
Author / Afflication
A. Chitra

Sunrise University, Alwar, India.
N. Senthilkumar

JKKMMRF’s College of Pharmacy, B. Komarapalayam, Tamilnadu, India.
M. Asraf Ali

Sunrise University, Alwar, India.
Keywords
Antibacterial ,Antifungal ,Catunaregum spinosa ,
Abstract

This study was carried out with an objective to evaluate the antibacterial and antifungal potential of methanolic extract of Catunaregum spinosa (MECS). Antibacterial activity of MECS was carried out against three Gram negative bacteria – Escherichia coli, Klebsiella pneumonia and Pseudomonas aeruginosa and two Gram positive bacteria – Bacillus Subtilis and Staphylococcus aureus. The antifungal activity of the extracts was evaluated on two common pathogenic fungi – Aspergillus niger and Candida albicans. The testing was done by the agar plate method. Zones of inhibition of extracts were compared with that of standard Chloramphenicol for antibacterial activity and Nystatin for antifungal activity. The extracts showed antibacterial and antifungal activities comparable with that of standard against the organisms tested. The results showed that the inhibition of the bacterial growth was more pronounced on E.coli and S. aureus as compared to the other tested organisms. Both the extracts showed the antifungal activity against C. albicans.

Volume / Issue / Year

4 , 2 , 2014

Starting Page No / Endling Page No

123 - 125