D.P. Khandale

P.J. Khinchi1

A.M. Chilke
Nonylphenol, Serum, Metabolites, Ophiocephalus. ,

Variations in the blood parameters are the direct reflection of unusual metabolism of the cells or tissues in the body of inflicted organisms. In the present study, total protein, cholesterol and glucose in the serum of Ophiocephalus punctatus was literally increased on exposure to sub-lethal concentrations of NP LC-50. It is inferred that it may be due dysfunctions of various organs impacted by NP. The NP would have increased the metabolism of proteins, cholesterol and glycogen that led to release of protein, cholesterol and glucose in the circulation for its ultimate use by the other demanding cells and tissues of the body. Cholesterol got shoot up consistently might be due to its synthesis and not getting converted into other steroidal products. Elevation in serum glucose level could be due to glycogenolysis and hepatic and/or pancreatic dysfunction.

8 , 1 ,