e ISSN- 2249-7668

Print ISSN- 2249-7676

ISSN

2249-7676

e ISSN

2249-7668

Publisher

pharmacology and toxicology

EVALUATION OF DRUG UTILIZATION PATTERN OF ANTIBIOTICS USED IN UPPER AND LOWER RESPIRATOERY TRACT INFECTION IN A TERTIARY CARE HOSPITAL
Author / Afflication
Sreelakshmi PS

Nehru College of Pharmacy Palakkad, Kerala, India
Puranik DS

Nehru College of Pharmacy Palakkad, Kerala, India
Wasiullah M

Parul University Vadodara, Gujarat, India
Sivakumar P

Nehru College of Pharmacy Palakkad, Kerala, India
Prashant Chandra

Nehru College of Pharmacy Palakkad, Kerala, India
Keywords
Evaluation ,Azithromycin And Ceftriaxone ,Demographics ,Defined Daily Dose ,Drug Utilization Pattern ,Antibiotics ,
Abstract

The study aims at evaluating the drug utilization pattern of antibiotics in patients with upper respiratory tract infection in a tertiary care hospital. Objectives: Present study is based on drug utilization pattern of different antibiotics used in upper respiratory tract infection comprises generating data on prescribing pattern in patient and compare PDD with DDD established by World Health Organization. Study covers study of antibiotics, average number of drugs per prescription, estimation the usage pattern and consumption of different antibiotics, find out the most frequently prescribed antibiotic for the particular type of respiratory tract infection, frequently used treatment combination along with the antibiotics and study about the various type of respiratory tract infections. Recording patient demographic parameters. analyses of prescribing patterns of the antibiotic at departmental level using icd classification of disease, atc classification of drugs and ddd as research tools, utilization of antibiotics will be measured in terms of defined daily dose/ 100 bed days (ddd per 100 bed days), descriptive statistical analysis is carried out. Study was conducted atpk das institute of medical sciences, aniyamkulam, after obtaining the permission of ethical committee, study design (prospective observational study ) duration of study (six month) sources of data (physicians prescribing records, patient’s medication records, discharges summaries parameters for evaluation (demographics of the patient, past history of respiratory tract infection, clinical investigations parameters, diagnostic report, medication details, study population patients of all age groups with respiratory tract infection admitted or provided with ambulatory care by the dept. of pulmonary medicine of the hospital. study based on inclusion and exclusion criteria. Result and Conclusion: Respiratory tract infection in general can cause restricted activities like loss of time from work and school etc. Along with this inappropriate and excessive treatment of these infections will contribute to the resistance of susceptible pathogens and this can lead to the re-hospitalization of patients. The reason for admission to hospitals might be the recurrent infection as the chief complaints but almost patients were treated with the same or alternative antibiotics without any culture or sensitivity tests. In this study most of the cases were not assessed by sputum culture, antibiotic sensitivity test and lung function test. This type of treatment was mainly seen in patients with non specific URTI. DU studies have the potential to make objective evaluation and analysis of health professionals work and provide a feedback to stimulate thinking about the practice and looking for ways to improve the performance. In this study most of the drugs were prescribed by brand name. Prescribing by generic name helps the hospital pharmacy to have better inventory control. Generic drugs are more economic than branded one and this can be easily affordable by the patients. More over that many drugs are selected from NLEM. From the results it was found that most commonly used antibiotic was Azithromycin and Ceftriaxone for the treatment of both upper and lower respiratory tract infection.

Volume / Issue / Year

8 , 2 , 2018

Starting Page No / Endling Page No

33 - 44